1. PI3K/Akt/mTOR
  2. mTOR
  3. OXA-01

OXA-01 是有效的 mTORC1mTORC2 抑制剂,其 IC50 值分别为 29 nM 和 7 nM。

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OXA-01 Chemical Structure

OXA-01 Chemical Structure

CAS No. : 936889-68-8

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规格 价格 是否有货 数量
1 mg ¥670
3 - 4 周
5 mg   询价  
10 mg   询价  

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查看 mTOR 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC50 values of 29 nM and 7 nM, respectively[1].

体内研究
(In Vivo)

OXA-01 demonstrated broad anti-tumor activity in several different human xenograft models of various histologies. Furthermore, in GEO and Colo-205 colon xenograft models, OXA-01 demonstrated 100% TGI, whilst rapamycin treatment resulted in only 75% and 53% TGI, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

409.87

Formula

C21H20ClN5O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

OXA-01 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
OXA-01
目录号:
HY-111065
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