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  3. PAT1inh-A0030

PAT1inh-A0030 是一种选择性 PAT1 (SLC26A6) 抑制剂 (IC50= 1.0 μM)。PAT1inh-A0030 在肠道液体吸收闭环模型中,抑制野生型和囊性纤维化 (CF) 小鼠 (CftrdelF508/delF508) 回肠的液体吸收。PAT1inh-A0030 可用于 CF 相关肠道疾病的研究。

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PAT1inh-A0030 Chemical Structure

PAT1inh-A0030 Chemical Structure

CAS No. : 1030097-65-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PAT1inh-A0030 is a selective PAT1 (SLC26A6) inhibitor (IC50= 1.0 μM). PAT1inh-A0030 inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption. PAT1inh-A0030 can be used in the study of intestinal diseases related to CF[1].

IC50 & Target

PAT1 (SLC26A6)[1].

分子量

326.35

Formula

C17H18N4O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

PAT1inh-A0030 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PAT1inh-A0030
目录号:
HY-162033
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