2. 天然产物
  3. 植物 黄酮类
  4. 胡麻科 异黄酮
  5. 芝麻
  6. Pedaliin

Pedaliin 是从芝麻 (Sesamum indicum L) 叶 (SLs) 的乙醇提取物中提取的一种生物活性成分。Pedaliin 具有体外抗氧化和抗结肠癌作用，具有自由基清除活性和铁还原抗氧化能力 (FRAP)。

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Pedaliin Chemical Structure

Pedaliin Chemical Structure

CAS No. : 22860-72-6

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1 mg ￥3500
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Pedaliin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP)[1][2].

体外研究
(In Vitro)

Pedaliin (0-35 μM; 72 h) dose-dependently attenuates the growth of human colon cancer cells, HT29 and HCT116[1].
Pedaliin (3.5-35 μM; 30 min; 37 ℃) has ferric reducing antioxidant power (FRAP)[1].
Pedaliin (7 μM; 48 h) alleviates invasion and migration of HT29 and HCT116 cells in non-cytotoxic conditions[1].
Pedaliin (20 μL) shows high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, oxygen radical absorbance capacity (ORAC), and in vitro antiglycation activities, and inhibits BSA glycation with an IC50 value of 41.8 μM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pedaliin 相关抗体:

Cell Viability Assay[1]

Cell Line: HCT116 cells
Concentration: 0, 3.5, 7, 17.5, and 35 μM
Incubation Time: 48 hours or 72 hours
Result: Inhibited cell growth (72 h) by 24% at 3.5-35 µM, invasion (48 h) by 18% at 7 µM, and migration (48 h) by 33% at 7 µM.
分子量

478.40

Formula

C22H22O12
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥99.0%

COA (197 KB)

产品使用指南 (1538 KB)
参考文献

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pedaliin22860-72-6OthersSesamum indicum Lantioxidantanti-colon cancerHT29HCT116Inhibitorinhibitorinhibit

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