1. Anti-infection
  2. Antibiotic
  3. Phleomycin D1

Phleomycin D1  (Synonyms: PLM D1)

目录号: HY-111428 纯度: 99.40%
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Phleomycin D1 (PLM D1) 是一种糖肽类抗生素,是 Bleomycin/Phleomycin 家族的成员。Phleomycin D1 通过结合和切割 DNA 导致细胞死亡。Phleomycin D1 诱导细胞周期停滞在 S 期。

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Phleomycin D1

Phleomycin D1 Chemical Structure

CAS No. : 11031-11-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA. Phleomycin D1 induces cell cycle arrest at S phase[1][2][3].

IC50 & Target

Glycopeptide

 

体外研究
(In Vitro)

Phleomycin D1 (10、20、40、80 µg/mL;12 小时) 诱导细胞周期停滞在 S 期[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis[3]

Cell Line: HDF-3 fibroblasts
Concentration: 10, 20, 40, 80 µg/mL
Incubation Time: 12 h
Result: Induced cell cycle arrest at S phase in a dose-dependent manner.
分子量

1427.52

Formula

C55H86N20O21S2

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Phleomycin D1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Phleomycin D1
目录号:
HY-111428
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