Procaterol hydrochloride  (Synonyms: 盐酸丙卡特罗)

Procaterol hydrochloride is a selective intermediate-acting β2 adrenoreceptor agonist with an EC₅₀ of 12.9 µM^[1]. Procaterol hydrochloride can inhibit inflammation both in vivo and in vitro^[2].

Procaterol treat inflammation through inhibiting oxidative stress in vitro^[2].
Procaterol (25-200 nM) increases the viability of 16HBE cells^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Procaterol significantly increases conditioned stimulus (CS)-evoked freezing levels^[3]. Propranolol-mediated blockade of β-adrenergic receptors (β-ARs) significantly reduces behavioral expression of Pavlovian threat conditioning (PTC), whereas systemic activation of β2-ARs using Procaterol enhances it^[3].
Procaterol hydrochloride is freshly dissolved in 0.9% sterile saline immediately prior to injections^[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

326.82

C₁₆H₂₃ClN₂O₃

62929-91-3

盐酸丙卡特罗

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. C Atgié, et al. Role of beta1- and beta3-adrenoceptors in the regulation of lipolysis and thermogenesis in rat brown adipocytes. Am J Physiol. 1997 Oct;273(4):C1136-42.  [Content Brief]

  [2]. Zheng Deng, et al. Procaterol but not dexamethasone protects 16HBE cells from H₂O₂-induced oxidative stress. J Pharmacol Sci. 2014;125(1):39-50.  [Content Brief]

  [3]. Yiran Gu, et al. A brainstem-central amygdala circuit underlies defensive responses to learned threats. Mol Psychiatry. 2020 Mar;25(3):640-654.  [Content Brief]