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Protein kinase affinity probe 1 

目录号: HY-136219
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摩尔计算器

Protein kinase affinity probe 1 是一种新型的蛋白激酶亲和探针 (probe)，用于蛋白激酶 (PK) 的功能鉴定。Protein kinase affinity probe 1 是一种改良的 Purvalanol B (HY-18299) 探针，带有 50% 的珠子负载 (化合物 S3)。

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Protein kinase affinity probe 1 Chemical Structure

Protein kinase affinity probe 1 Chemical Structure

CAS No. : 2098621-90-8

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Protein kinase affinity probe 1 相关抗体

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生物活性

Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3)[1].

体外研究
(In Vitro)

“S” indicates that the PKI (Purvalanol B) is sepharose-bound[1].
In a series of pull-down experiments from the lysates of HeLa cells, the effects of 0.1, 0.5, 1, 2, 5, 10, 25, and 50% loadings of PK inhibitors is determined. Examine higher bead loadings (75 and 100%) are prevented due to lack of compound solubility and poor reproducibility of the synthesis outcomes. 50% loading is the highest feasible in this study[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Protein kinase affinity probe 1 相关抗体:
分子量

531.09

Formula

C26H39ClN8O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Protein kinase affinity probe 1 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Protein kinase affinity probe 12098621-90-8Protein kinase affinity probe1Protein kinase affinity probe-1OthersprobePKIPKsepharoseaffinityHeLaInhibitorinhibitorinhibit

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Protein kinase affinity probe 1
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HY-136219
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