2. Immunology/Inflammation
  3. FAP
  4. QI-18

QI-18 是一种成纤维细胞激活蛋白 (FAP) 抑制剂，其 IC50 值为 0.50 nM，相较于 UAMC-1110（HY-100684, IC50 3.25 nM），其活性提高了 6.5 倍。 QI-18 可用于合成具有高肿瘤选择性和高剂量的放射性示踪剂，用于肿瘤的诊断与治疗。

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QI-18

QI-18 Chemical Structure

CAS No. : 3093894-38-0

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QI-18 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

QI-18 is a fibroblast activation protein (FAP) inhibitor with the IC50 of 0.50 nM, which is a 6.5-fold increase in potency over that of UAMC-1110 (HY-100684，IC50 of 3.25 nM). QI-18 can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1].

分子量

647.59

Formula

C31H27F2N7O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

QI-18 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QI-183093894-38-0QI18QI 18FAPFibroblast activation proteinU87MGfibroblast activation protein inhibitorcancer imagingInhibitorinhibitorinhibit

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目录号：
HY-159934
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