1. NF-κB
    Neuronal Signaling
    Membrane Transporter/Ion Channel
  2. NF-κB
    Amyloid-β
    nAChR
  3. (R)-(+)-Anatabine

(R)-(+)-Anatabine 

目录号: HY-126047B
产品使用指南

(R)-(+)-Anatabine 是一种 Anatabine 低活性的 S 型异构体。Anatabine 是一种有效的 α4β2 nAChR 激动剂。Anatabine 通过阻止淀粉样蛋白前体蛋白的 β 裂解,抑制 NF-κB 激活,并降低淀粉样 β () 的产生。Anatabine 具有抗炎作用,可用于神经退行性疾病的研究。

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(R)-(+)-Anatabine Chemical Structure

(R)-(+)-Anatabine Chemical Structure

CAS No. : 126454-22-6

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(R)-(+)-Anatabine 的其他形式现货产品:

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Description

(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent α4β2 nAChR agonist[1]. Anatabine inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment[2][3][4].

Molecular Weight

160.22

Formula

C₁₀H₁₂N₂

CAS No.

126454-22-6

SMILES

[C@H]1(C2=CC=CN=C2)CC=CCN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(R)-(+)-AnatabineNF-κBAmyloid-βnAChRNuclear factor-κBNuclear factor-kappaBβ-amyloid peptideAbetaNicotinic acetylcholine receptorsLess-activeR-enantiomerAnatabineα4β2Inhibitorinhibitorinhibit

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产品名称:
(R)-(+)-Anatabine
目录号:
HY-126047B
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