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  4. (R)-Thionisoxetine

(R)-Thionisoxetine  (Synonyms: LY-368975)

目录号: HY-118064
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摩尔计算器

(R)-Thionisoxetine 是一种有效的选择性中枢和外周去甲肾上腺素 (NE) 摄取抑制剂。(R)-thionisoxetine 可防止 6-羟基多巴胺导致的下丘脑 NE 耗竭，ED50 为 0.21 mg/kg。(R)-Thionisoxetine 可用于多种疾病的研究，包括抑郁症和尿失禁。

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(R)-Thionisoxetine Chemical Structure

(R)-Thionisoxetine Chemical Structure

CAS No. : 163059-33-4

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(R)-Thionisoxetine 相关抗体

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  • 生物活性

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生物活性

(R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence[1].

IC50 & Target

ED50: 0.21 mg/kg (prevented hypothalamic NE depletion)[1]
分子量

287.42

Formula

C17H21NOS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(R)-Thionisoxetine 相关分类

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Keywords:

(R)-Thionisoxetine163059-33-4LY-368975LY368975LY 368975Othersnorepinephrine uptakehypothalamic NEdepressionurinary incontinenceneuronal norepinephrine (NE)Inhibitorinhibitorinhibit

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