2. Others GPCR/G Protein
  3. Isotope-Labeled Compounds G2A (GPR132)
  4. (±)11(12)-EET methyl ester-d11

(±)11(12)-EET methyl ester-d11  (Synonyms: 11,12-EET methyl ester-d11; (±)11,12-EpETrE methyl ester-d11)

目录号: HY-139938S
产品使用指南 技术支持

(±)11(12)-EET-d11 methyl ester (11,12-EET methyl ester-d11)是 (±)11(12)-EET methyl ester (HY-139938) 的氘代物。(±)11(12)-EET methyl ester 是一种环氧二十碳三烯酸 (EET)。EET 是一种内源性脂质信号分子，具有心脏保护和血管扩张作用。(±)11(12)-EET methyl ester 可与 GPR132 结合并激活 GPR132。(±)11(12)-EET methyl ester 可增强小鼠和斑马鱼的造血诱导和移植功能。

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(±)11(12)-EET methyl ester-d<sub>11</sub>

(±)11(12)-EET methyl ester-d11 Chemical Structure

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规格 是否有货
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Other Forms of (±)11(12)-EET methyl ester-d11:

(±)11(12)-EET methyl ester-d11 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(±)11(12)-EET-d11 methyl ester (11,12-EET methyl ester-d11) is the deuterium labeled (±)11(12)-EET methyl ester (HY-139938). (±)11(12)-EET methyl ester is a type of epoxyeicosatrienoic acid (EET). EETs are endogenous lipid signaling molecules with cardioprotective and vasodilatory actions. (±)11(12)-EET methyl ester binds to and activates GPR132. (±)11(12)-EET methyl ester enhances hematopoietic induction and engraftment in mice and zebrafish[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(±)11(12)-EET methyl ester-d11 相关抗体:
分子量

345.56

Formula

C21H23D11O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(±)11(12)-EET methyl ester-d11 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)11(12)-EET methyl ester-d1111,12-EET methyl ester-d11(±)11,12-EpETrE methyl ester-d11Isotope-Labeled CompoundsG2A (GPR132)GPR132EETInhibitorinhibitorinhibit

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