2. Anti-infection
  3. Fungal
  4. (±)-Pinoresinol

(±)-Pinoresinol 是一种有效的抗真菌剂。(±)-Pinoresinol 具有抗真菌活性。

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(±)-Pinoresinol

(±)-Pinoresinol Chemical Structure

CAS No. : 4263-88-1

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(±)-Pinoresinol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BV-2 IC50
31.1 μM
Compound: 9; Pinoresinol
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 26774654]
BV-2 IC50
76.19 μM
Compound: 20
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
[PMID: 28911817]
HepG2 IC50
51 nM
Compound: 47
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 37847948]
Neutrophil IC50
1.3 μg/mL
Compound: 20
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced superoxide anion generation by measuring superoxide dismutase SOD-inhibitable ferricytochrome c reduction incubated for 5 mins before fMLP/CB stimulation for 3 mins by spectrophotometry
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced superoxide anion generation by measuring superoxide dismutase SOD-inhibitable ferricytochrome c reduction incubated for 5 mins before fMLP/CB stimulation for 3 mins by spectrophotometry
[PMID: 28218000]
Neutrophil IC50
> 10 μg/mL
Compound: 20
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release pre-incubated for 5 mins before fMLP/CB stimulation using MeO-Suc-Ala-Ala-Pro-Val-pnitroanilide as substrate
Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release pre-incubated for 5 mins before fMLP/CB stimulation using MeO-Suc-Ala-Ala-Pro-Val-pnitroanilide as substrate
[PMID: 28218000]
PANC-1 IC50
37.5 μM
Compound: 7
Cytotoxicity against human PANC1 cells after 72 hrs by WST8 assay
Cytotoxicity against human PANC1 cells after 72 hrs by WST8 assay
[PMID: 28495081]
体外研究
(In Vitro)

(±)-Pinoresinol 显示抗真菌活性，对 Fusarium verticillioides 的 MIC 值为 1.0 mg/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(±)-Pinoresinol 相关抗体:
分子量

358.39

Formula

C20H22O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(±)-Pinoresinol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Pinoresinol4263-88-1FungalInhibitorinhibitorinhibit

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