2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Ralfinamide mesylate

Ralfinamide mesylate  (Synonyms: FCE-26742A mesylate)

目录号: HY-101437A
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摩尔计算器

Ralfinamide mesylate (FCE-26742A mesylate) 是一种口服可利用，来源于 α-aminoamide 的钠离子通道阻滞剂, 可用于缓解疼痛的研究。

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Ralfinamide mesylate Chemical Structure

Ralfinamide mesylate Chemical Structure

CAS No. : 202825-45-4

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Ralfinamide mesylate 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

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生物活性

Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain[1][2].

IC50 & Target

Na+channel[1]
体内研究
(In Vivo)

Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 81 adult male Sprague–Dawley male rats (260–460 g)[1]
Dosage: 80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)
Administration: Oral gavage; twice daily; until postoperative day 42
Result: Suppressed neuropathic pain.
Clinical Trial
分子量

398.45

Formula

C18H23FN2O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ralfinamide mesylate 相关分类

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Keywords:

Ralfinamide202825-45-4FCE-26742ASodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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