2. Anti-infection Immunology/Inflammation
  3. Bacterial CD28
  4. Reltecimod TFA

Reltecimod TFA  (Synonyms: AB-103 TFA)

目录号: HY-P1698B 纯度: 99.78%
COA 产品使用指南

摩尔计算器

Reltecimod (AB-103) TFA 是一种 T 细胞特异性表面糖蛋白 CD28 (TP44) 拮抗剂。Reltecimod TFA 对不同的细菌感染、细菌外毒素和内毒素以及电离辐射都有良好的抗性作用。Reltecimod TFA 通过靶向和减弱关键的 CD28/B7-2 共刺激通路来调节炎症反应，而不抑制它。Reltecimod TFA 可用于研究坏死性软组织感染 (NSTIs)。

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Custom Peptide Synthesis

Reltecimod TFA Chemical Structure

Reltecimod TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 mg ￥406
In-stock
10 mg ￥650
In-stock
25 mg ￥1300
In-stock
50 mg ￥2100
In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Reltecimod TFA:

Reltecimod TFA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs)[1].

体内研究
(In Vivo)

Reltecimod (1.25-5 mg/kg; i.v.) TFA 可提高感染不同细菌的小鼠的存活率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

1037.19 (free base)

Formula

C46H72N10O15S.xC2HF3O2
性状

固体

颜色

White to off-white

Sequence

Ala-Ser-Pro-Met-Leu-Val-Ala-Tyr-Asp-Ala
Sequence Shortening

ASPMLVAYDA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Reltecimod TFA 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ReltecimodAB-103AB103AB 103BacterialCD28NSTIsTP44T cellE. coliStreptococcus pyogenesCecal ligation and punctureCLPInhibitorinhibitorinhibit

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目录号：
HY-P1698B
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