1. Apoptosis
  2. RIP kinase
  3. RIPK3-IN-2

RIPK3-IN-2 是 RIP3 抑制剂。RIPK3-IN-2 可用于由激活的坏死途径引起或与之相关的疾病研究。

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RIPK3-IN-2 Chemical Structure

RIPK3-IN-2 Chemical Structure

CAS No. : 2665669-32-7

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Customer Review

查看 RIP kinase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research[1].

体外研究
(In Vitro)

RIPK3-IN-2 (0.3-20 μM; 42 h) inhibits HT-29 cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 14 h) inhibits MEF cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 18 h) inhibits L929 cell growth[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HT-29 cells
Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM
Incubation Time: 42 hours
Result: Showed EC50 value of 0.085 μM.

Cell Viability Assay[1]

Cell Line: MEF cells
Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM
Incubation Time: 14 hours
Result: Showed EC50 value of 0.24 μM.

Cell Viability Assay[1]

Cell Line: L929 cells
Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM
Incubation Time: 18 hours
Result: Showed EC50 value of 0.21 μM.
分子量

441.95

Formula

C21H16ClN3O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RIPK3-IN-2
目录号:
HY-148052
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