1. Metabolic Enzyme/Protease
  2. ROR
  3. RORγt agonist 1

RORγt agonist 1 

目录号: HY-126321
产品使用指南

RORγt agonist 1 (compound 14) 是有效的,口服生物可利用的 RORγt 激动剂,EC50 为 20.8 nM。RORγt agonist 1 显示出高代谢稳定性,改善的水溶性和优异的小鼠 PK 特征。RORγt agonist 1 是用于癌症免疫疗法的 RORγt 激动剂的潜在候选物。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

RORγt agonist 1 Chemical Structure

RORγt agonist 1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
1 mg   Get quote  
5 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8 nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy[1].

IC50 & Target

EC50: 20.8 nM (RORγt)[1]

In Vivo

RORγt agonist 1 shows high metabolic stability (t1/2 = 113 min) in mouse liver microsome and has improved aqueous solubility at pH 7.4[1].

Molecular Weight

545.45

Formula

C₂₄H₁₇F₆NO₅S

SMILES

FC1=CC(OC(F)F)=CC(C2=CC=C(CC(CC(O)=O)N3S(C4=CC(C(F)(F)F)=CC=C4)(=O)=O)C3=C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
RORγt agonist 1
目录号:
HY-126321
需求量:

RORγt agonist 1

Cat. No.: HY-126321