2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. RORγt agonist 2

RORγt agonist 2 是一种有效的 RORγt 激动剂。RORγt agonist 2 促进 Th17 细胞分化，提高促炎细胞因子水平，从而增加淋巴细胞的细胞毒性。RORγt agonist 2 抑制调节性 T 细胞的产生，从而抑制免疫反应 (提取自专利 WO2021136339A1，化合物 17)。

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RORγt agonist 2 Chemical Structure

RORγt agonist 2 Chemical Structure

CAS No. : 2663787-92-4

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RORγt agonist 2 相关抗体

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  • 生物活性

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生物活性

RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17)[1].

分子量

585.64

Formula

C30H30F3N3O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RORγt agonist 2 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RORγt agonist 22663787-92-4RORγt agonist2RORγt agonist-2RORRAR-related orphan receptorRORγtTh17 cellspro-inflammatory cytokinescytotoxicitylymphocytesT cellsInhibitorinhibitorinhibit

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