2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel Autophagy Apoptosis
  3. PPAR TRP Channel Autophagy Ferroptosis
  4. Rosiglitazone maleate (Standard)

Rosiglitazone maleate (Standard)  (Synonyms: 马来酸罗格列酮 (标准品); BRL 49653C (Standard))

目录号: HY-14600R 纯度: ≥98%
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Rosiglitazone (maleate) (Standard) 是 Rosiglitazone (maleate) 的分析标准品。本产品用于研究及分析应用。 Rosiglitazone maleate (BRL 49653C) 是一种有效的，选择性的 PPARγ 激活剂，对 PPARγ1，PPARγ2 和 PPARγ 的 EC50 值分别为 30 nM，100 nM 和 60 nM，对 PPARγ 的 Kd 值约为 40 nM；Rosiglitazone maleate 同时为 TRP channels 的调节剂，可抑制 TRPM2, TRPM3 的活性，激活 TRPC5。

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Rosiglitazone maleate (Standard) Chemical Structure

Rosiglitazone maleate (Standard) Chemical Structure

CAS No. : 155141-29-0

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生物活性

Rosiglitazone (maleate) (Standard) is the analytical standard of Rosiglitazone (maleate). This product is intended for research and analytical applications. Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

分子量

473.50

Formula

C22H23N3O7S
CAS 号
中文名称

马来酸罗格列酮 (标准品)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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Rosiglitazone maleate (Standard) 相关分类

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Keywords:

Rosiglitazone maleate (Standard)155141-29-0BRL 49653C (Standard)马来酸罗格列酮 (标准品)PPARTRP ChannelAutophagyFerroptosisPeroxisome proliferator-activated receptorsTransient receptor potential channelsInhibitorinhibitorinhibit

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