1. Screening Libraries
  2. Stem Cell Signaling Compound Library

干细胞化合物库 - Stem Cell Signaling Compound Library

Cat. No.: HY-L017
Library Contents: XLSX PDF SDF

成体干细胞具有自我更新和无限分化的潜能,对组织的稳态和再生具有重要作用。干细胞自我更新潜能主要体现在干细胞多次或无限分化能力上。一些信号通路如 Notch,Wnt,Hedgehog 信号通路及Polycomb 蛋白家族参与了干细胞的自我更新过程。近年来的研究主要集中在肿瘤干细胞 (CSCs)、诱导多能干细胞 (iPSCs)、神经干细胞和胚胎干细胞多能性的维持等方面。其中,肿瘤干细胞被认为是肿瘤发生、生长和复发的原因,对癌症治疗具有重要意义。

MCE 收录了 355 个小分子化合物,可以用于干细胞调控及信号通路研究。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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  • Description

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Description
& Advantages

•   A unique collection of 355 small molecule inhibitors with biological activity used for stem cell regulatory and signaling pathway research.

•   Targets such as GSK-3, Hedgehog, Notch, JAK, ROCK, Wnt, γ-secretase, Casein Kinase, etc.

•   A powerful tool for researching the mechanism behind stem cells, regenerative therapy, drug screening based on tumor stem cells, as well as other pharmaceutical and biological applications.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some protein kinase inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Rich documentation with structure, IC50, and customer reviews.

•   NMR and HPLC validated to ensure the highest purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 355 stem cell signaling related compounds supplied as pre-dissolved DMSO solutions or Solid .
Solution: 348 compounds supplied in 10 mM solution, 6 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Stem Cell Signaling Compound Library

Source: MedChem Express

Contents of Stem Cell Signaling Compound Library
Documentation

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    产品名称:
    Stem Cell Signaling Compound Library
    目录号:
    HY-L017
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack