1. 一站式药筛
  2. 化合物库
  3. 天然产物化合物库系列
  4. 中药相关化合物库
  5. FDA 中药单体化合物库
FDA 中药单体化合物库 - FDA-Approved Traditional Chinese Medicine Active Compound Library

Cat. No.: HY-L163

中药为药物化合物提供了丰富的自然资源,这些资源通常被认为可有效且安全地用于药物发现。中药基于“多成分、多靶点、多途径”的原理,天然具有多药理作用。作为草药,中草药中的次生植物代谢产物在缓解传统医学和民间使用中的多种疾病方面发挥着重要作用。所以,中药衍生化合物的鉴定也是药物开发的重要过程,也是解剖中药整体作用机制的必要因素。FDA 上市化合物已经完成了广泛的临床前和临床研究,具有良好的生物活性、安全性和生物利用度。

MCE 收录了 324 种 FDA 上市的中药单体化合物,包括含黄酮类、多酚类、生物碱、萜类等多种结构类型,是一种很好的药物再利用工具,也是筛选中药来源药物的有用工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE FDA 中药单体化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,309 个产品以 10 mM 浓度提供,8 个产品以 2 mM 浓度提供,7 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 324 FDA traditional Chinese medicine active compounds for high throughput screening (HTS) and high content screening (HCS).

•    The compounds in the library contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes.

•   A useful tool for drug discovery.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Compounds have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 324 FDA-approved traditional Chinese medicine active compounds supplied as pre-dissolved Solutions or Solid
Solution: 309 compounds supplied in 10 mM solution, 8 compounds supplied in 2 mM solution, 7 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

COX (11)

HIV (5)

HSV (4)

PPAR (4)

AMPK (3)

HBV (3)

Akt (2)

FGFR (2)

HSP (2)

IKK (2)

mTOR (2)

PKC (2)

STAT (2)

COMT (1)

EGFR (1)

FXR (1)

HCV (1)

HDAC (1)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    FDA-Approved Traditional Chinese Medicine Active Compound Library
    目录号:
    HY-L163
    需求量: