1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 疾病相关化合物库
  5. 抗炎中药单体化合物库
抗炎中药单体化合物库 - Anti-inflammatory Traditional Chinese Medicine Active Compound Library

Cat. No.: HY-L114

炎症通过激活免疫系统、局部血管系统和受损组织内的各种细胞来促进生理和病理过程。越来越多的流行病学和临床证据表明,慢性炎症与各种人类疾病有因果关系,包括心脑血管疾病、关节疾病、皮肤病、肺相关疾病、血液病、肝脏疾病、肠道疾病以及糖尿病。

各种来自传统中药的天然产物已被证明可以安全地抑制促炎途径和控制炎症相关疾病。MCE收录了1060 种具有抗炎活性的中药单体化合物,来源于黄连、板蓝根、金银花、连翘等中药。MCE抗炎中药单体化合物库是从中药中发现抗炎药物的有效工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 抗炎中药单体化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1032 个产品以 10 mM 浓度提供,23 个产品以 2 mM 浓度提供,5 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1060 compounds for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-inflammatory drugs.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 1060 anti-inflammatory Traditional Chinese Medicine active compounds supplied as pre-dissolved Solutions or Solid
Solution: 1032 compounds supplied in 10 mM solution, 23 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

NF-κB (155)

COX (79)

Akt (29)

ERK (29)

STAT (27)

PPAR (21)

MMP (17)

PI3K (17)

JNK (14)

EGFR (13)

HIV (13)

HBV (8)

HSV (8)

PARP (8)

JAK (7)

mTOR (7)

PKC (7)

AMPK (6)

Wnt (6)

CXCR (4)

SOD (4)

GLUT (3)

HDAC (3)

IKK (3)

Src (3)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Anti-inflammatory Traditional Chinese Medicine Active Compound Library
    目录号:
    HY-L114
    需求量: