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细胞重编程化合物库 - Reprogramming Compound Library

Cat. No.: HY-L039
Library Contents: XLSX PDF SDF

细胞重编程技术为药物筛选,疾病模型建立,人造器官发育及细胞治疗带来新的希望。自从 2006 年Yamanaka 利用 OCT4,SOX2,KLF4,及 c-MYC 四种细胞因子成功将体细胞重编程为多能干细胞(iPSCs)以来,重编程技术已经得到突飞猛进的发展。尽管已发展出有效的细胞重编程技术,但大多数方法仍不适合临床应用,因为这些方法存在整合外源基因或使用致癌基因的风险。基于 miRNA、非病毒基因、非整合载体和小分子化合物诱导作为可替代的方法,已经被作为可能的解决方案。这些替代方法中,小分子化合物在临床应用中最具有潜力。使用小分子化合物对细胞进行重编程,成本低,比较容易控制作用浓度和时间,并且小分子化合物具有较高的细胞渗透性,易于合成和标准化,适合大规模细胞的生产。

MCE 重编程化合物库包含 1193 种小分子化合物,这些化合物主要作用于细胞重编程相关的信号通路,是诱导细胞重编程的潜在刺激物。MCE重编程化合物库是研究细胞重编程和再生医学的重要工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 细胞重编程化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1174 个产品以 10 mM 浓度提供,19 个产品以 2 mM 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock
2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

Get quote In-stock

Please contact us at

sales@MedChemExpress.cn

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  • Description

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Description
& Advantages

•   A unique collection of 1193 reprogramming compounds for high throughput screening (HTS) and high content screening (HCS).

•   Epigenetic modifiers, metabolism regulators, cell senescence alleviators and signaling pathway modulators such as Wnt activators, MET activators, Hedgehog activators are included.

•   A useful tool for the research of reprogramming.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 1193 reprogramming compounds supplied as pre-dissolved Solutions or Solid
Solution: 1174 compounds supplied in 10 mM solution, 19 compounds supplied in 2 mM solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Reprogramming Compound Library

Source: MedChem Express

Documentation

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    产品名称:
    Reprogramming Compound Library
    目录号:
    HY-L039
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Storage Tubes with Rack