2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Succinate Dehydrogenase
  4. SDH-IN-14

SDH-IN-14 (Compound Z2) 是琥珀酸脱氢酶 SDH 的抑制剂。对灰霉病菌有抗真菌活性 (EC50=2.7 μg/mL)。SDH-IN-14 通过破坏细胞壁和细胞膜的完整性发挥作用。

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SDH-IN-14 Chemical Structure

SDH-IN-14 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

SDH-IN-14 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH). SDH-IN-14 has antifungal activity (EC50=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane[1].

体外研究
(In Vitro)

SDH-IN-14 (0-100 μg/mL; 12 h) 处理灰霉病菌，发现随着浓度的增加，细胞膜通透性增强[1]。
SDH-IN-14 (0-200 μg/mL; 10 h) 处理灰霉病菌，发现 MDA 含量随浓度增加而增加，细胞膜受到氧化损伤[1]。
SDH-IN-14 (12.5-100 μg/mL; 24 h) 处理灰霉病菌，发现浓度依赖性的抑制了 SDH 活性[1]。
SDH-IN-14 (100 μg/mL) 的抗真菌抑制率分别为 96.7% (B.cinerea); 52.6% (R.solani); 69.9% (P.capsici); 59.2% (=S.sclerotiorum); 34.5% (=F.graminearum); 70.6% (Tomato Botrytis cinerea); 15.0% (=F.asiaticum)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SDH-IN-14 相关抗体:
体内研究
(In Vivo)

SDH-IN-14 (100; 200 μg/mL) 在蓝莓叶片上表现出良好的抗真菌活性，优于 Azoxystrobin (HY-B0849) 和 Fluopyram (HY-119459)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

424.54

Formula

C21H20N4O2S2
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SDH-IN-14 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDH-IN-14FungalSuccinate Dehydrogenaseindole1,3,4-thiadiazoleantifungal activityBotrytis cinereaInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-161504
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