2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Succinate Dehydrogenase
  4. SDH-IN-15

SDH-IN-15 (Compound 5e) 是琥珀酸脱氢酶 SDH 的抑制剂 (IC50=2.04 μM)。SDH-IN-15 具有显著的抗真菌活性。SDH-IN-15 通过抑制 SDH，阻断真菌的线粒体呼吸链，导致真菌死亡。

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SDH-IN-15 Chemical Structure

SDH-IN-15 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

SDH-IN-15 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC50=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death[1].

体外研究
(In Vitro)

SDH-IN-15 的抗真菌活性分别为 EC50=0.039 μg/mL (R. solani); 0.426 μg/mL (S. sclerotiorum); 3.482 μg/mL (B. cinerea) 。优于 Boscalid (HY-119976) 和 Fluxapyroxad (HY-135549)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SDH-IN-15 相关抗体:
体内研究
(In Vivo)

SDH-IN-15 (100 μg/mL; 5 天) 对水稻叶片上的立枯丝核菌的生长具有显著的抑制效果，保护效率达 86.8 %，明显优于对照药物 Boscalid (HY-119976) (68.1 %) 和 Fluxapyroxad (HY-135549) (80.6 %)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

477.30

Formula

C21H19BrF2N4O2
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SDH-IN-15 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDH-IN-15FungalSuccinate DehydrogenaseSDHIspyrazole-4-carboxamidesoxime etheroxime esterantifungal activitiesantifungal mechanismInhibitorinhibitorinhibit

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目录号：
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