2. Peptides
  3. Selcopintide

Selcopintide  (Synonyms: Cpne7-DP)

目录号: HY-P3386
产品使用指南

摩尔计算器

Selcopintide (Cpne7-DP) 由一个与 hCPNE7 蛋白的 10 个氨基酸残基 344-353 片段相对应的合成肽组成。Selcopintide 通过上调成牙本质细胞标记基因、DSPP 和巢蛋白高度再现 CPNE7 的体外作用。Selcopintide 促进不同程度牙本质缺损的牙本质再生，再生后的硬组织表现出真牙本质的特征。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Selcopintide acetate 通常具有更好的水溶性和稳定性。

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Selcopintide Chemical Structure

Selcopintide Chemical Structure

CAS No. : 2130912-34-2

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Selcopintide 的其他形式现货产品:

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Other Forms of Selcopintide:

Selcopintide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Selcopintide (Cpne7-DP) consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin[1].

体外研究
(In Vitro)

Selcopintide (Cpne7-DP) 直接穿透成牙本质细胞 (MDPC-23 细胞)[1]。
Selcopintide (1, 10 μg) 以剂量依赖性方式增加 dspp 启动子活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Selcopintide 相关抗体:
体内研究
(In Vivo)

Selcopintide (Cpne7-DP; 10 µg 在 0.5% 纤维蛋白凝胶中与人 DPC 细胞混合后皮下移植) 在浅腔和深腔模型中促进牙本质样组织形成和管状牙本质和牙本质小管闭塞的再生[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Immunocompromised mice (NIH-bg-nu-xid)[1]
Dosage: 10 µg
Administration: Subcutaneous transplantation in a 0.5% fibrin gel
Result: Promotes dentin-like tissue formation.
Promotes the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models.
分子量

1384.63

Formula

C62H105N21O15
CAS 号
Sequence

Lys-Tyr-Lys-Gln-Lys-Arg-Arg-Ser-Tyr-Lys
Sequence Shortening

KYKQKRRSYK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Selcopintide2130912-34-2Cpne7-DPOthersodontoblastic cellCPNE7-derived peptidetubular orthodentinperitubular dentin formationInhibitorinhibitorinhibit

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