1. Membrane Transporter/Ion Channel
  2. SGLT
  3. SGL5213

SGL5213是一种有效的、口服有效的、低吸收性钠依赖性葡萄糖协同转运蛋白 1 (SGLT1)的抑制剂,其对 hSGLT1 和hSGLT2 的IC50 值分别为 29 nM 和 20 nM。SGL5213 可用于 2 型糖尿病的研究。

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SGL5213 Chemical Structure

SGL5213 Chemical Structure

CAS No. : 1240305-17-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].

IC50 & Target

IC50: 29nM/20 nM (hSGLT1/ hSGLT2)[1].

分子量

669.85

Formula

C37H55N3O8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SGL5213 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SGL5213
目录号:
HY-114308
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