2. MAPK/ERK Pathway
  3. KLF
  4. Sp1-IN-1

Sp1-IN-1 是一种选择性特异性蛋白 1 (Sp1) 抑制剂。Sp1-IN-1 抑制 Hela 细胞和 MCF-7 细胞的增殖。Sp1-IN-1 可用于宫颈癌和乳腺癌的研究。

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Sp1-IN-1

Sp1-IN-1 Chemical Structure

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Sp1-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sp1-IN-1 is a selective specificity protein 1 (Sp1) inhibitor. Sp1-IN-1 inhibits the proliferation of Hela cells and MCF-7 cells. Sp1-IN-1 can be used to the studies of cervical cancer and breast cancer[1].

体外研究
(In Vitro)

Sp1-IN-1 (Compound I8) 抑制 Hela 和 MCF-7 细胞增殖，IC50 分别为 10.56 和 11.77 μM[1]。
Sp1-IN-1 (3-12 μM，48 小时) 剂量依赖性地下调 MCF-7 细胞中 Sp1 蛋白的表达[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sp1-IN-1 相关抗体:

Western Blot Analysis[1]

Cell Line: MCF-7 cells
Concentration: 3, 6, 12 μM
Incubation Time: 48 h
Result: Dose-dependently down-regulated the expression of Sp1 protein.
分子量

578.82

Formula

C37H54O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sp1-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sp1-IN-1KLFKrüppel-like factorSp1 inhibitorAsiatic acidAntitumor activityInhibitorinhibitorinhibit

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产品名称：
Sp1-IN-1
目录号：
HY-178143
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