1. Metabolic Enzyme/Protease Apoptosis
  2. Endogenous Metabolite Apoptosis
  3. Stachyose hydrate

Stachyose hydrate  (Synonyms: 水苏糖)

目录号: HY-N0299 纯度: 98.0%
COA 产品使用指南 技术支持

Stachyose hydrate 是一种具有口服活性的益生元,可增强有益细菌的生长和活性。Stachyose hydrate 具有降血糖作用的,并可用过调节肠道微生物改善炎症。此外 Stachyose hydrate 可诱导植物细胞凋亡 (Apoptosis)。Stachyose hydrate 可用于炎症。胃肠道疾病以及农业领域研究。

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Stachyose hydrate

Stachyose hydrate Chemical Structure

CAS No. : 54261-98-2

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5 mg ¥150
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10 mg ¥250
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50 mg ¥500
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100 mg ¥700
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500 mg ¥1700
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1 g ¥2720
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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis (Apoptosis). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture [1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Stachyose hydrate (3.2 mg/mL, 36 小时, 48 小时) 在 Nicotiana benthamiana 叶片细胞中诱导细胞凋亡样的程序性细胞死亡,表现为 DNA 断裂[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[3]

Cell Line: Nicotiana benthamiana leaf cells (tobacco, plant)
Concentration: 3.2 mg/mL
Incubation Time: 36 h, 48 h
Result: Resulted in nuclear DNA fragmentation.
Induced apoptotic-like programmed cell death.
体内研究
(In Vivo)

Stachyose hydrate (200, 400, 600 mg/kg, 口服, 每日一次, 共 3 周) 缓解 DSS (HY-116282C) 诱导的溃疡性结肠炎 C57BL/6J 小鼠的结肠炎症状,恢复肠道屏障完整性,并调节促炎和抗炎细胞因子的表达 [2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: DSS (HY-116282C)-induced ulcerative colitis C57BL/6J mouse model[2]
Dosage: 200, 400, 600 mg/kg
Administration: Oral gavage (p.o.), once daily for 3 weeks
Result: Significantly alleviated colitis symptoms in DSS-induced colitis mice, including reducing weight loss, lowering disease activity index (DAI), and increasing colon length, while restoring colonic epithelial barrier integrity.
Dose-dependently upregulated mRNA expression of ZO-1, Claudin-1, and Occludin, reduced IL-17, TNF-α, IL-1β, and IL-6 expression, and increased IL-10 levels.
Clinical Trial
Formula

C24H42O21.xH2O

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

H2O 中的溶解度 : 125 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: 98.0%

参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Stachyose hydrate
目录号:
HY-N0299
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