2. Metabolic Enzyme/Protease
  3. Stearoyl-CoA Desaturase (SCD)
  4. Sterculic acid

Sterculic acid  (Synonyms: 苹婆酸)

目录号: HY-127143 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Sterculic acid 是一种硬脂酰辅酶 A 去饱和酶 1 (SCD1) 抑制剂。Sterculic acid 特异性抑制 delta-9 去饱和酶 (Δ9D) 活性，IC50 值为 0.9 μM。

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Sterculic acid Chemical Structure

Sterculic acid Chemical Structure

CAS No. : 738-87-4

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规格 价格 是否有货 数量
25 mg ￥9000
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Sterculic acid 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1].

IC50 & Target[1]

delta-9 desaturase

0.9 μM (IC50)

体外研究
(In Vitro)

Sterculic acid (SA) is a cyclopropene fatty acid originally found in the seeds of the plant Sterculia foetida with numerous biological activities[2].
Sterculic acid is able to reduce adrenomedullin expression (AP, RP, APS, IML, in preparation)[2].
Sterculic acid is also able to mediate anti-inflammatory and protective effects[2].
Sterculic acid has a potent luteolytic effect in ovines by inhibition in the synthesis of progesterone, which causes luteal regression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sterculic acid 相关抗体:
体内研究
(In Vivo)

Sterculic acid has been proposed as a potential tool for the treatment of metabolic syndrome (MS) since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1) in vivo[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

294.47

Formula

C19H34O2
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

苹婆酸
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

Methanol 中的溶解度 : 10 mg/mL (33.96 mM; 超声助溶 (<60°C))

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.3959 mL 16.9797 mL 33.9593 mL
5 mM 0.6792 mL 3.3959 mL 6.7919 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥99.0%

COA (159 KB)

产品使用指南 (1538 KB)
参考文献

Sterculic acid 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
Methanol 1 mM 3.3959 mL 16.9797 mL 33.9593 mL 84.8983 mL
5 mM 0.6792 mL 3.3959 mL 6.7919 mL 16.9797 mL
10 mM 0.3396 mL 1.6980 mL 3.3959 mL 8.4898 mL
15 mM 0.2264 mL 1.1320 mL 2.2640 mL 5.6599 mL
20 mM 0.1698 mL 0.8490 mL 1.6980 mL 4.2449 mL
25 mM 0.1358 mL 0.6792 mL 1.3584 mL 3.3959 mL
30 mM 0.1132 mL 0.5660 mL 1.1320 mL 2.8299 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sterculic acid738-87-4苹婆酸Stearoyl-CoA Desaturase (SCD)sterculic acidinflammationmetabolic syndromestearoyl-CoA desaturase-1SCD1delta-9 desaturaseΔ9DInhibitorinhibitorinhibit

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目录号：
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