2. Immunology/Inflammation
  3. STING
  4. STING modulator-3

STING modulator-3 是一种 STING 抑制剂。在闪烁接近实验中，STING modulator-3 抑制 R232 STING 的 Ki 值为 43.1 nM。STING modulator-3 对 THP-1 细胞的 IRF-3 激活和 TNF-β 诱导无影响。

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STING modulator-3 Chemical Structure

STING modulator-3 Chemical Structure

CAS No. : 2839639-94-8

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STING modulator-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells[1].

体外研究
(In Vitro)

STING modulator-3 (AIP01) (10 μM；3 h，24 h) 分别不影响处理 THP-1 细胞 3 h 时，IRF-3 的磷酸化或是处理 24 h 时，对 TNF-β 的诱导[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

STING modulator-3 相关抗体:
分子量

375.39

Formula

C18H17N9O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

STING modulator-3 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STING modulator-32839639-94-8STING modulator3STING modulator 3STINGStimulator of Interferon GenesTMEM173MITAERISMPYSInhibitorinhibitorinhibit

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STING modulator-3
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