2. Immunology/Inflammation
  3. Macrophage migration inhibitory factor (MIF)
  4. TE-11

TE-11 是一种 MIF 互变异构酶抑制剂，IC50 为 5.63 μM。TE-11 可改善类克罗恩病性结肠炎，减少 MIF 诱导的嗜酸性粒细胞和中性粒细胞迁移，并防止 M1 型极化及相关的代谢重编程。

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TE-11

TE-11 Chemical Structure

CAS No. : 160488-11-9

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TE-11 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming[1].

体外研究
(In Vitro)

TE-11 (20 µM) 在没有直接抗氧化作用的情况下，抑制 M1 型活化巨噬细胞中促炎性细胞因子和反应性氧氮物种 RONS 的产生[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

TE-11 相关抗体:
体内研究
(In Vivo)

TE-11 (5, 10 mg/kg; ip; once every day for 4 days) 可改善由 TNBS 诱导的小鼠结肠炎[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

235.28

Formula

C16H13NO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TE-11 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TE-11160488-11-9TE11TE 11Macrophage migration inhibitory factor (MIF)MIFtautomerase,TNBSInhibitorinhibitorinhibit

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产品名称：
TE-11
目录号：
HY-173624
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