1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Thiamine pyrophosphate tetrahydrate

Thiamine pyrophosphate tetrahydrate 是维生素 B1 的辅酶形式,是丙酮酸脱氢酶复合物和酮戊二酸脱氢酶复合物的必需中间体。Thiamine pyrophosphate tetrahydrate 作为 α-酮酸脱氢酶的辅助因子,是氧化磷酸化和戊糖磷酸途径所必需的。

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Thiamine pyrophosphate tetrahydrate

Thiamine pyrophosphate tetrahydrate Chemical Structure

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100 mg   询价  
250 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Thiamine pyrophosphate tetrahydrate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate tetrahydrate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases[1][2][3].

体内研究
(In Vivo)

Thiamine pyrophosphate (25 mg/kg,腹腔注射) tetrahydrate 抑制大鼠卵巢组织缺血再灌注诱导的氧化损伤[1]
Thiamine pyrophosphate (20 mg/kg,腹腔注射,每天一次,持续 14 天) tetrahydrate 可预防顺铂 (HY-17394) 诱导的大鼠心脏毒性以及相关的氧化应激和心脏损伤[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thiamine pyrophosphate tetrahydrate
目录号:
HY-E70624
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