2. Anti-infection
  3. Antibiotic Bacterial
  4. Ticarcillin

Ticarcillin  (Synonyms: 替卡西林)

目录号: HY-139805
产品使用指南

摩尔计算器

Ticarcillin 是一种半合成的、广谱的、羧基青霉素类抗菌剂，对革兰氏阳性球菌，包括链球菌和葡萄球菌有活性。Ticarcillin 对大多数革兰氏阴性生物，包括绿脓杆菌也有效。Ticarcillin 可用于下呼吸道感染、皮肤和皮肤结构感染、尿路感染和腹腔内感染研究。

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Ticarcillin Chemical Structure

Ticarcillin Chemical Structure

CAS No. : 34787-01-4

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规格 是否有货
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Other Forms of Ticarcillin:

Ticarcillin 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research[1][2][3].

IC50 & Target

β-lactam

 

体外研究
(In Vitro)

Ticarcillin treatment (10 mg/L; 18 h) shows antibacterial activities[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ticarcillin 相关抗体:

Cell Viability Assay[2]

Cell Line: Ps. aeruginosa
Concentration: 10 mg/L
Incubation Time: 18 hours
Result: Showed the MIC for Ticarcillin against strain between 6.3-12.5 mg/L.
体内研究
(In Vivo)

Ticarcillin (Subcutaneous injection; 50, 100, 200 mg/kg; once) treatment shows a dose-dependent antibacterial effect[2].
Ticarcillin (Subcutaneous injection; 50, 100, 200 mg/kg; once) treatment shows excellent pharmacokinetic assessment[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss type male mice injected with Ps. aeruginosa[2]
Dosage: 50, 100, 200 mg/kg
Administration: Subcutaneous injection; 50, 100, 200 mg/kg; once
Result: Increased effect significantly (0.001 < P < 0.0025) with increasing dose.
Animal Model: Swiss type male mice injected with Ps. aeruginosa[2]
Dosage: 50, 100, 200 mg/kg
Administration: Subcutaneous injection; 50, 100, 200 mg/kg; once
Result:
Dose (mg/kg) AUCa (mg/kg) Kelb (h-1) T1/2 (min)
Ticarcillin 50 8.76 (0.72) 1.57 (0.18) 26
100 26.14 (0.60) 1.53 (0.11) 27
200 54.56 (2.90) 1.47 (0.12) 28
分子量

384.43

Formula

C15H16N2O6S2
CAS 号
中文名称

替卡西林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ticarcillin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ticarcillin34787-01-4替卡西林AntibioticBacterialantibacterial agentgram-negative bacteriaATCC 27853Ps. aeruginosaInhibitorinhibitorinhibit

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