1. Autophagy Metabolic Enzyme/Protease
  2. p62 E1/E2/E3 Enzyme
  3. TRAF6 peptide

TRAF6 peptide 是一种特异性的 TRAF6-p62 相互作用抑制剂。TRAF6 peptide 能消除 NGF 依赖性 TrkA 泛素化。TRAF6 peptide 在诸如阿尔茨海默症 (AD)、帕金森、ALS、头部外伤、癫痫和中风等神经系统性疾病中具有较好的研究潜力。

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Custom Peptide Synthesis

TRAF6 peptide Chemical Structure

TRAF6 peptide Chemical Structure

CAS No. : 852805-92-6

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TRAF6 peptide 的其他形式现货产品:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].

体外研究
(In Vitro)

TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1].
TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: PC12 cells
Concentration: 150 µM
Incubation Time: 5 h
Result: Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.
分子量

3161.64

Formula

C145H238N34O44

CAS 号
Sequence Shortening

AAVALLPAVLLALLAPESASGPSEDPSVNFLK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TRAF6 peptide
目录号:
HY-P3709
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