1. 多肽产品
  2. 多肽及其衍生物
  3. 抑制剂与底物肽
  4. Urantide

Urantide 是一种选择性和竞争性的尿紧张素-II (UT) 受体拮抗剂肽 (pKB=8.3),可阻断大鼠体外胸主动脉中人尿紧张素-II (hU-II) 诱导的收缩。Urantide 可以用于研究 hU-II 在哺乳动物心血管系统中 (病理) 生理作用。

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Custom Peptide Synthesis

Urantide Chemical Structure

Urantide Chemical Structure

CAS No. : 669089-53-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide can be used to study the (patho)physiological role of hU-II in the mammalian cardiovascular system[1].

IC50 & Target

urotensin-II Receptor (UT Receptor)[1].

分子量

1075.26

Formula

C51H66N10O12S2

CAS 号
Sequence

Asp-{Pen}-Phe-{d-Trp}-{Orn}-Tyr-Cys-Val (Disulfide bridge: Pen2-Cys7)

Sequence Shortening

D-{Pen}-F-{d-Trp}-{Orn}-YCV (Disulfide bridge: Pen2-Cys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Urantide
目录号:
HY-108055
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