2. 寡核苷酸
  3. 反义寡核苷酸
  4. Vupanorsen

Vupanorsen  (Synonyms: IONIS ANGPT-L3Rx; ISIS 703802)

目录号: HY-153497
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摩尔计算器

Vupanorsen 是一种抑制 Angiopoietin-like 3 (ANGPTL3) 蛋白合成的反义寡核苷酸。Vupanorsen 降低甘油三酯和导致动脉粥样硬化的脂蛋白。

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DNA, d([2′-O-(2-methoxyethyl)]rG-sp-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rA-T-sp-T-sp-G-sp-m5C-sp-m5C-sp-A-sp-G-sp-T-sp-A-sp-A-sp-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-sp-[2′-O-(2-methoxyethyl)]m5rC-sp-[2′-O-(2-methoxyethyl)]rA), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate]

Vupanorsen Chemical Structure

CAS No. : 2097587-62-5

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规格 价格 是否有货 数量
1 mg ￥5340
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Other Forms of Vupanorsen:

Vupanorsen 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.

Clinical Trial
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

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  • 稀释计算器

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Keywords:

Vupanorsen2097587-62-5IONIS ANGPT-L3Rx ISIS 703802ISIS703802ISIS 703802ISIS-703802OthersInhibitorinhibitorinhibit

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