2. 寡核苷酸
  3. 反义寡核苷酸
  4. Vupanorsen sodium

Vupanorsen sodium  (Synonyms: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium)

目录号: HY-153497A
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Vupanorsen (sodium) 是一种抑制 Angiopoietin-like 3 (ANGPTL3) 蛋白合成的反义寡核苷酸。Vupanorsen (sodium) 降低甘油三酯和导致动脉粥样硬化的脂蛋白。

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DNA, d([2′-O-(2-methoxyethyl)]rG-sp-[2′-O-(2-methoxyethyl)]rG-[2′-O-(2-methoxyethyl)]rA-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rA-T-sp-T-sp-G-sp-m5C-sp-m5C-sp-A-sp-G-sp-T-sp-A-sp-A-sp-[2′-O-(2-methoxyethyl)]m5rU-[2′-O-(2-methoxyethyl)]m5rC-[2′-O-(2-methoxyethyl)]rG-sp-[2′-O-(2-methoxyethyl)]m5rC-sp-[2′-O-(2-methoxyethyl)]rA), 5′-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate], sodium salt (1:20)

Vupanorsen sodium Chemical Structure

CAS No. : 2172852-12-7

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Vupanorsen sodium 的其他形式现货产品:

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Vupanorsen sodium 相关抗体

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  • 生物活性

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生物活性

Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.

Clinical Trial
分子量

9105.04

Formula

C296H414N86Na20O15P20S13
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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Keywords:

Vupanorsen2172852-12-7IONIS ANGPT-L3RxISIS 703802ISIS703802ISIS-703802OthersInhibitorinhibitorinhibit

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