1. GPCR/G Protein
  2. Formyl Peptide Receptor (FPR)
  3. WRW4 TFA

WRW4 TFA 是一种特异的甲酰肽受体样 1 (FPRL1) 拮抗剂,抑制 WKYMVm 与 FPRL1 的 IC50 为 0.23 μM。WRW4 TFA 抑制 FPRL1 激动剂 MMK-1、淀粉样 β 42 (Abeta42) 肽和F肽引起的细胞内钙的增加。

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Custom Peptide Synthesis

WRW4 TFA Chemical Structure

WRW4 TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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WRW4 TFA 的其他形式现货产品:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WRW4 TFA, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 TFA specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide[1].

体外研究
(In Vitro)

WRW4 TFA inhibits Abeta42 peptide-induced superoxide generation and chemotactic migration of neutrophils, and also completely inhibits the internalization of Abeta42 peptide in human macrophages. WRW4 TFA specifically blocks ERK phosphorylation downstream of FPRL1 by WKYMVm[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1218.29

Formula

C63H66F3N15O8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
WRW4 TFA
目录号:
HY-P1119A
需求量: