2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. Antibody-Drug Conjugates (ADCs) CD276/B7-H3
  4. YL201

YL201 是一种靶向 B7H3 的抗体-药物偶联物 (ADC)。YL201 包含人源抗 B7H3 单克隆抗体 Tambotatug (HY-P991719)、可被蛋白酶切割的连接子 DL-01 (HY-155870) 或 DL-01 甲酸盐 (HY-155870A)，以及拓扑异构酶 1 抑制剂有效载荷。YL201 可用于研究表达 B7H3 的晚期实体瘤，重点包括广泛期小细胞肺癌 (ES-SCLC)、鼻咽癌 (NPC)、非小细胞肺癌、食管鳞状细胞癌。

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YL201

YL201 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
1 mg ￥9450
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5 mg 询价 询问价格 & 货期

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Customer Review

YL201 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

YL201 is an antibody-drug conjugate (ADC) targeting B7H3. YL201 comprises a human anti-B7H3 monoclonal antibody Tambotatug (HY-P991719), a protease-cleavable linker DL-01 (HY-155870) or DL-01 formic (HY-155870A), and a topoisomerase 1 inhibitor payload. YL201 can be used for the study of B7H3-expressing advanced solid tumors, with a focus on extensive-stage small cell lung cancer (ES-SCLC), nasopharyngeal carcinoma (NPC), non-small cell lung cancer, esophageal squamous cell carcinoma[1][2].

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

YL201 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YL201YL 201YL-201Antibody-Drug Conjugates (ADCs)CD276/B7-H3Antibody-Drug ConjugatesB7 homolog 3 proteinextensive-stage small cell lung cancer (ES-SCLC)nasopharyngeal carcinoma (NPC)non-small cell lung canceresophageal squamous cell carcinomaB7H3ADCInhibitorinhibitorinhibit

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产品名称：
YL201
目录号：
HY-177572
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