1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Zorevunersen

Zorevunersen  (Synonyms: STK-001)

目录号: HY-148410
产品使用指南

Zorevunersen (STK-001) 是一种反义寡核苷酸,通过提高 SCN1A mRNA 水平从而增强钠通道 Nav1.1 蛋白的表达。Zorevunersen 用于 Dravet 综合征的研究。

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RNA, (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5U-m5U-G-G-A-G-m5C-A-A-G-A-m5U-m5U-A-m5U-m5C)

Zorevunersen Chemical Structure

CAS No. : 2415330-04-8

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  • 生物活性

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生物活性

Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome.

IC50 & Target

Nav1.1

 

分子量

6682.39

Formula

C204H263N63O114P20S20

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Zorevunersen
目录号:
HY-148410
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