1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. α-Glucosidase-IN-30

α-Glucosidase-IN-30 (compound 8c) 是一种强有力的、具有口服活性、竞争性的 α-葡萄糖苷酶(α-glucosidase) 抑制剂,其Ki 值为40.0 µM, IC50 值为 49.0 µM。α-Glucosidase-IN-30 对 MCF-7 和 HDF 细胞系没有细胞毒性,可用于 2 型糖尿病研究。

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α-Glucosidase-IN-30 Chemical Structure

α-Glucosidase-IN-30 Chemical Structure

CAS No. : 2966859-35-6

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki  of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study[1].

IC50 & Target

49.0 µM (α-glucosidase)

体外研究
(In Vitro)

α-Glucosidase-IN-30 (compound 8c) 对 MCF-7和 HDF 细胞系 (IC50 > 200 μM) 均无细胞毒活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

389.41

Formula

C20H19N7O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

α-Glucosidase-IN-30 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
α-Glucosidase-IN-30
目录号:
HY-155105
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