1. Metabolic Enzyme/Protease
  2. Glucosidase
  3. α-Glucosidase-IN-43

α-Glucosidase-IN-43 (compound AS14) 是 α-葡萄糖苷酶抑制剂 (IC50: 4.32 μM),具有急性降血糖活性。α-Glucosidase-IN-43 具有安全性和体内效力,它对小鼠正常成纤维细胞无毒,并能够拯救链脲佐菌素 (HY-13753) 诱导糖尿病大鼠。α-Glucosidase-IN-43 可用于糖尿病患者餐后高血糖的研究。

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α-Glucosidase-IN-43 Chemical Structure

α-Glucosidase-IN-43 Chemical Structure

CAS No. : 3018963-27-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50: 4.32 μM) with acute hypoglycemic activity. α-Glucosidase-IN-43 exhibits safety and in vivo efficacy, is nontoxic to normal mouse fibroblasts, and is able to rescue streptozotocin (HY-13753)-induced diabetic rats. α-Glucosidase-IN-43 can be used to study postprandial hyperglycemia in diabetic patients[1].

IC50 & Target

IC50: 4.32 μM (α-Glucosidase)[1]

分子量

461.55

Formula

C27H31N3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

α-Glucosidase-IN-43 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
α-Glucosidase-IN-43
目录号:
HY-163005
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