1. Metabolic Enzyme/Protease
  2. Glycosidase
  3. α-Glucosidase-IN-92

α-Glucosidase-IN-92 (compound 14b) 是一种靶向 α-葡萄糖苷酶 (α-glucosidase) 的非竞争性抑制剂 (IC50=64.0 μM),抑制效力优于 Acarbose (HY-B0089) (IC50=750 μM)。α-Glucosidase-IN-92 具备良好的口服生物利用度,能够通过血脑屏障。α-Glucosidase-IN-92 可延缓碳水化合物水解、降低餐后血糖。α-Glucosidase-IN-92 可用于 2 型糖尿病的抗糖研究。

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α-Glucosidase-IN-92

α-Glucosidase-IN-92 Chemical Structure

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     可免费申领三个不同产品的试用装。

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Glucosidase-IN-92 (compound 14b) is a non-competitive inhibitor targeting α-glucosidase (IC50=64.0 μM), with better inhibitory potency than Acarbose (HY-B0089) (IC50=750 μM). α-Glucosidase-IN-92 has good oral bioavailability and can cross the blood-brain barrier. α-Glucosidase-IN-92 can delay carbohydrate hydrolysis and reduce postprandial blood glucose. α-Glucosidase-IN-92 can be used in anti-glycemic research for type 2 diabetes[1].

IC50 & Target

α‑glucosidase

 

分子量

515.57

Formula

C30H25N7O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

α-Glucosidase-IN-92 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
α-Glucosidase-IN-92
目录号:
HY-176221
需求量: