2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-7

11β-HSD1-IN-7 (compound c10a) 是 11β‑HSD1 的抑制剂，对人 11β‑HSD1 的 IC50 值为 1.9 μM。11β-HSD1-IN-7 可以用于糖尿病和认知衰退的研究。

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11β-HSD1-IN-7 Chemical Structure

11β-HSD1-IN-7 Chemical Structure

CAS No. : 728-86-9

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5 g ￥480
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11β-HSD1-IN-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11β-HSD1-IN-7 (compound c10a) is a 11β‑HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β‑HSD1. 11β-HSD1-IN-7 can be used for the research of diabetes and cognitive decline[1].

IC50 & Target

IC50: 1.9 μM (human 11β‑HSD1)[1]
体外研究
(In Vitro)

11β-HSD1-IN-7 (0-50 μM) inhibits human and rat 11β‑HSD1 with IC50 values of 1.9 μM and ＞50 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

11β-HSD1-IN-7 相关抗体:
分子量

250.22

Formula

C14H9F3O
CAS 号
性状

固体

颜色

White to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 99.73%

COA (169 KB) HNMR (123 KB) RP-HPLC (192 KB)

产品使用指南 (1538 KB)
参考文献

11β-HSD1-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-7728-86-911β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseF-MRSdiabetescognitive declineglucocorticoidhumanInhibitorinhibitorinhibit

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