2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK
  3. Peptide-Drug Conjugates (PDCs) Ephrin Receptor
  4. (123B9)2-L2-PTX

(123B9)2-L2-PTX 是一种 EphA2 激动剂肽-药物偶联物 (PDC)。(123B9)2-L2-PTX 由二聚体 123B9 (HY-P10579) 和 Paclitaxel (HY-B0015) 组成。(123B9)2-L2-PTX 可显著减少循环肿瘤细胞，并抑制乳腺癌转移小鼠模型中的肺部肿瘤转移。(123B9)2-L2-PTX 可用于癌症研究，例如黑色素瘤、卵巢癌和乳腺癌。

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Custom Peptide Synthesis

(123B9)2-L2-PTX Chemical Structure

(123B9)2-L2-PTX Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

(123B9)2-L2-PTX 相关抗体

Top Publications Citing Use of Products

查看 Ephrin Receptor 亚型特异性产品:

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EphA

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(123B9)2-L2-PTX is an EphA2-agonistic peptide-drug conjugate (PDC). (123B9)2-L2-PTX consists of a dimeric 123B9 (HY-P10579) and Paclitaxel (HY-B0015). (123B9)2-L2-PTX significantly reduces circulating tumor cells and inhibits lung tumor metastasis in breast-cancer-Metastasis mice model. (123B9)2-L2-PTX can be used for cancers research, such as melanomas and ovarian and breast cancers[1].

IC50 & Target

EPHA2

 

分子量

4155.16

Formula

C192H254Cl2F2N34O63
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(123B9)2-L2-PTX 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(123B9)2-L2-PTXPeptide-Drug Conjugates (PDCs)Ephrin ReceptorEphA2Peptide-drug conjugateAgonisticMDA-MB-231 cellsBreast-cancer-Metastasis mice modelMelanomasOvarian cancerBreast cancerInhibitorinhibitorinhibit

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目录号：
HY-P11018
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