2. 天然产物
  3. 疾病研究领域 海洋天然产物 黄酮类 微生物
  4. 心血管 海洋微生物 其他黄酮类
  5. 2,3,4,6,8-Pentahydroxy-1-methylxanthone

2,3,4,6,8-Pentahydroxy-1-methylxanthone 

目录号: HY-N12166
产品使用指南

摩尔计算器

2,3,4,6,8-Pentahydroxy-1-methylxanthone 是 Wardomyces anomalus 的山酮衍生物。2,3,4,6,8-Pentahydroxy-1-methylxanthone 具有显著的抗氧化活性。2,3,4,6,8-Pentahydroxy-1-methylxanthone 是 p56lck 酪氨酸激酶抑制剂。2,3,4,6,8-Pentahydroxy-1-methylxanthone 能够用于治疗心血管疾病的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

2,3,4,6,8-Pentahydroxy-1-methylxanthone Chemical Structure

2,3,4,6,8-Pentahydroxy-1-methylxanthone Chemical Structure

CAS No. : 548740-87-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

2,3,4,6,8-Pentahydroxy-1-methylxanthone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease[1].

IC50 & Target

p56 lck[1]
体外研究
(In Vitro)

2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞对 ox-LDL 诱导的细胞凋亡具有保护作用[2]。
2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞抑制 ox-LDL 诱导的 VECs粘附分子表达[2]。
2,3,4,6,8-Pentahydroxy-1-methylxanthone (1~50µM, 50µg/mL ox-LDL, 6h) 在人脐静脉内皮细胞对ox-LDL 引起的氧化损伤有保护作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2,3,4,6,8-Pentahydroxy-1-methylxanthone 相关抗体:

Apoptosis Analysis[2]

Cell Line: Human umbilical vein endothelial cells
Concentration: 1µM, 5µM, 50µM (with 50 µg/mL ox-LDL)
Incubation Time: 6h
Result: The percentage of apoptosis cells significantly decreased to around 20 ~ 40%.

Western Blot Analysis[2]

Cell Line: Human umbilical vein endothelial cells
Concentration: 1µM, 5µM, 50µM (with 50 µg/mL ox-LDL)
Incubation Time: 6h
Result: The level of pro-apoptotic protein Bax decreased significantly, while that of anti-apoptotic protein Bcl-2 increased significantly.

Apoptosis Analysis[2]

Cell Line: Human umbilical vein endothelial cells
Concentration: 1µM, 5µM, 50µM (with 50 µg/mL ox-LDL)
Incubation Time: 6h
Result: The protein level of VCAM-1 and ICAM-1 decreased.

Immunofluorescence[2]

Cell Line: Human umbilical vein endothelial cells
Concentration: 1µM, 5µM, 50µM (with 50 µg/mL ox-LDL)
Incubation Time: 6h
Result: Activated Nrf2 nuclear translocations and the expression of HO-1 was significantly increased.
分子量

290.23

Formula

C14H10O7
CAS 号
结构分类
初始来源

Arthrinium sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,3,4,6,8-Pentahydroxy-1-methylxanthone548740-87-0OthersHUVECsNtioxidantApoptosisInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
2,3,4,6,8-Pentahydroxy-1-methylxanthone
目录号：
HY-N12166
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z