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  3. 4-Aminosalicylic acid hemicalcium

4-Aminosalicylic acid hemicalcium 是二氢叶酸还原酶(DHFR)的抑制剂,也是一种抗结核药。4-Aminosalicylic acid hemicalcium 具有抗炎活性,可用于炎症性肠病 (IBD) 的研究。4-Aminosalicylic acid hemicalcium 具有口服活性。

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4-Aminosalicylic acid hemicalcium Chemical Structure

4-Aminosalicylic acid hemicalcium Chemical Structure

CAS No. : 133-15-3

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4-Aminosalicylic acid hemicalcium 的其他形式现货产品:

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Aminosalicylic acid hemicalcium is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid hemicalcium exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid hemicalcium is orally active[1][1][3].

体外研究
(In Vitro)

4-Aminosalicylic acid hemicalcium 通过二氢叶酸合酶 (DHPS) 和二氢叶酸合酶 (DHFS) 进入叶酸途径,生成羟基二氢叶酸抗代谢物,进而抑制二氢叶酸还原酶 (DHFR) 酶活性[1]
4-Aminosalicylic acid hemicalcium 可抑制结核分枝杆菌 M. tuberculosis H37Rv 的生长,MIC 值为 0.4 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

173.18

Formula

C7H7NO3.1/2Ca

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

4-Aminosalicylic acid hemicalcium 相关分类

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4-Aminosalicylic acid hemicalcium
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HY-22252
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