2. Anti-infection
  3. RSV
  4. VP-14637

MDT-637 (VP 14637) 是一种新型呼吸道合胞病毒融合 (respiratory syncytial virus (RSV) fusion) 抑制剂，IC50 值为1.42 ng/mL。

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VP-14637 Chemical Structure

VP-14637 Chemical Structure

CAS No. : 235106-62-4

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规格 价格 是否有货
1 mg ￥1296
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VP-14637 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

MDT-637 (VP 14637) is a novel respiratory syncytial virus (RSV) fusion inhibitor with an IC50 of 1.42 ng/mL.

IC50 & Target

IC50: 1.42 ng/mL (RSV)[1]
体外研究
(In Vitro)

MDT‐637 has broad in vitro antiviral activity on clinical strains of different RSV genotypes and clades. MDT-637 inhibits three laboratory strains (RSV-A Long, RSV-A2, and RSV-9320) and four clinical strains (RSV-Memphis-37, RSV-LAP0824, and RSV-HAN1135) with IC50s range from 0.36 to 3.4 ng/mL[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

VP-14637 相关抗体:
分子量

510.51

Formula

C25H22N10O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Cell Assay
[1]

The laboratory and clinical isolates of RSV and various concentrations (ranging from 0.1 μM to 31.6 pM) of MDT‐637 (or ribavirin) are added to the HEp-2 cell monolayers at the same time. After 72 hours of incubation at 37°C, the cells and supernatants are harvested. An aliquot is immediately serially diluted and used for plaque assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

VP-14637 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VP-14637235106-62-4MDT-637VP14637VP 14637MDT637MDT 637RSVRespiratory syncytial virusInhibitorinhibitorinhibit

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产品名称：
VP-14637
目录号：
HY-12994
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