2. Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein
  3. Calcium Channel 5-HT Receptor
  4. Nexopamil racemate

Nexopamil racemate  (Synonyms: 奈索帕米)

目录号: HY-101727
产品使用指南

摩尔计算器

Nexopamil racemate 是 Nexopamil 的外消旋体。Nexopamil 是体内血栓形成和体外血小板聚集中的一种联合 Ca2+/5-HT2 拮抗剂。

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Nexopamil racemate Chemical Structure

Nexopamil racemate Chemical Structure

CAS No. : 116759-35-4

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Nexopamil racemate 相关抗体

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查看 5-HT Receptor 亚型特异性产品:

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on thrombus formation in vivo and on platelet aggregation in vitro.

IC50 & Target

5-HT2 Receptor

 

体外研究
(In Vitro)

Serotonin-induced platelet aggregation in dog platelet-rich plasma (PRP) in vitro is most potently inhibited by Nexopamil (IC50 81 nM) [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Nexopamil racemate 相关抗体:
体内研究
(In Vivo)

Nexopamil (0.05 mg/kg) completely abolishes cyclic flow reductions (CFRs) during the first 30 min after application without significantly altering hemodynamics[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

404.59

Formula

C24H40N2O3
CAS 号
中文名称

奈索帕米
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nexopamil racemate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nexopamil116759-35-4奈索帕米Calcium Channel5-HT ReceptorCa2+ channelsCa channelsSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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