多肽修饰

多肽修饰通过修饰多肽主链及侧链结构，改变多肽的理化性质，进而改善其生物利用效率。MCE 配备强大的技术团队，可提供 300+ 种修饰，满足您多样化的研究需求。

N 端修饰

•Ac
•Allyl
•Cholesteryl-
•N-Propargylglycine-
•Fmoc
•Acryl
•Fructose-
•Ad
•CBZ
•Alloc
•Glucose-
•BPS-
•Boc
•Pyr
•DMAP-Ac
•Morpholine-4-carbonyl-
•Bz
•D-Pyr
•NTriAc
•Trans-Cinnamoyl
•Bz (5-NH₂,2-NO₂)
•LA-
•PhAc
•2-Furoyl
•Bz (4-F)
•Mpa-
•Py-Ac
•Methacryl-
•Bz (4-NO₂)
•Tos
•N-Amidinoglycine
•BPA-

C 端修饰

•-pNA
•-OMe
•-ONP
•-OSu
•-NH₂
•-OEt
•-AMC
•-NHMe
•-ol
•-OBzl
•-AFC
•-NHEt

脂肪酸化

•For
•MeOSuc
•5-Hexynoic acid
•F-Lau-
•MeOCO
•Iba
•Heptanedioic acid
•Myr-
•2-Br-Ac
•pentenoic acid
•Oct-
•F-Myr-
•2-Cl-Ac
•pentinoyl
•F-Oct-
•Pentadeconyl-
•2-I-Ac
•Hex-
•Dec-
•Pal-
•OH-Ac
•5-heptenoic acid
•Sebacic acid
•Cys (Pal)
•3-Bromopropionyl
•Trans-3-hexenoyl-
•F-Dec-
•Pam3C-
•But-
•Linoletic-
•Undecyl-
•Ste-
•Suc
•10,12-Pentacosadiynoic acid
•Lau-
•Octanedioic acid

甲基化

•Lys (Me)
•Arg (Me)
•Tyr (Me)
•Tyr (Et)
•Lys (Me₂)
•Arg (Me₂)asymmetrical
•Thr (Me)
•D-Tyr (Et)
•Lys (Me₃)
•Arg (Me₂) symmetrical
•Ser (Me)

磷酸化

•pSer
•D-pSer
•Di-sites in sequence
•4-sites in sequence
•pTyr
•D-pTyr
•Tri-sites in sequence
•5-sites in sequence
•pThr
•D-pThr

支肽

•Symmetric 2 Branches
•Symmetric 4 Branches
•Symmetric 8 Branches
•Lys symmetric 2 Branches
•Lys symmetric 4 Branches
•Lys symmetric 8 Branches
•Orn symmetric 2 Branches
•Orn symmetric 4 Branches
•Orn symmetric 8 Branches
•Glu 2 Branches (Pure)
•Glycerol 3 Branches ester
•Thr (Peptide2)
•Ser (Peptide2)
•Lys (Peptide2)

环肽

•Mono Disulfide bridge
•Double Disulfide bridge
•Triple Disulfide bridge
•Random Triple Disulfide bridge
•Same Sequence Inter-Disulfide bridge by Cys oxidation
•Different Sequence Inter-Disulfide bridge by Cys oxidation
•Oxidation between Se-Cys
•Amide Cyclic (end)
•Amide Cyclic (side chain) by Lys
•Amide Cyclic (side chain) by Orn

荧光/染料标记

•Biotin-
•FITC-
•Dansyl-
•Lys (Dnp)
•DeThioBiotin
•-ED-FITC
•-EDDansyl
•D-Lys (Dnp)
•-EDBiotin
•-Lys (FITC)-
•-Lys (Dansyl)-
•Dab (Dnp)
•Glu (Biotin-PEG2)
•-Lys (FITC)
•-Lys (Dansyl)
•Dap (Dnp)
•-Lys (Biotin)-
•Lys (Ahx-FITC)
•Dansli-e-Lys
•-EDDnp
•-Lys (Biotin)
•FITC-e-Lys
•Dansyl-Ahx-
•-Lys (LC-Biotin)-
•FITC-Ahx-
•5-FAM-
•-Lys (LC-Biotin)
•5-TAMRA-
•5,6-FAM
•Biotin-e-Lys
•5 (6)-TAMTA-
•6’FAM
•Lys (S-S-Biotin)
•-EDYAMRA
•-ED-5-FAM
•Biotin-Ahx-
•-Lys (TAMRA)-
•-Lys (5-FAM)-
•Orn (Bio)
•-Lys (5-TAMRA)
•Lys (5,6-FAM)
•MCA-
•5-TAMRA-e-Lys
•-Lys (5-FAM)
•-Lys (MCA)-
•5-TAMRA-Acp
•5-FAM-E-Lys
•-Lys (MCA)
•5-FAM-Ahx-
•Lys (MCA)-

BSA、KLH、OVA 偶联

•BSA-Peptide N terminus
•KLH-Peptide N terminus
•OVA-Peptide N terminus
•BSA-Peptide C terminus
•KLH-Peptide C terminus
•OVA-Peptide C terminus
•BSA-Peptide via Cys
•KLH-Peptide via Cys
•OVA-Peptide via Cys

Phe & Tyr 衍生物

•D-2-Cl-Phe
•D-4-F-Phe
•L-2-Me-Phe
•L-3-I-Tyr
•L-2-Cl-Phe
•L-4-F-Phe
•D-4-Me-Phe
•D-3,5-DiI-Tyr
•D-3-Cl-Phe
•D-4-NO₂-Phe
•L-4-Me-Phe
•L-3,5-DiI-Tyr
•L-3-Cl-Phe
•L-4-NO₂-Phe
•D-4-NH₂-Phe
•D-3-NO₂-Tyr
•D-4-Cl-Phe
•D-4-I-Phe
•L-4-NH₂-Phe
•L-3-NO₂-Tyr
•L-4-Cl-Phe
•L-4-I-Phe
•D-3-Cl-Tyr
•D-3,5-DiNO₂-Tyr
•D-3,4-DiCl-Phe
•D-3-CN-Phe
•L-3-Cl-Tyr
•L-3,5-DiNO₂-Tyr
•L-3,4-DiCl-Phe
•L-3-CN-Phe
•D-3,5-DiCl-Tyr
•L-3-F-Tyr
•D-4-Br-Phe
•D-4-CN-Phe
•L-3,5-DiCl-Tyr
•L-4-NO₂-Phg
•L-4-Br-Phe
•L-4-CN-Phe
•D-3,5-DiBr-Tyr
•D-4-NO₂-Phg
•D-3-F-Phe
•D-2-Me-Phe
•L-3,5-DiBr-Tyr
•L-3,5-DiF-Phe
•L-3-F-Phe
•D-3-I-Tyr

Linker

•Gly
•Ava
•AEA
•GABA
•Beta-Ala
•Ahx
•Ado
•Mini-PEG
•Mini-PEG2
•Mini-PEG3
•PEG4

树脂

•peptide on Wang Resin
•peptide on 2-CTC Resin
•peptide on Rink Amide AM Resin
•peptide on Rink Amide MBHA Resin

D 型氨基酸

•D-Ala
•D-Lys
•D-Glu
•D-Tyr
•D-Arg
•D-Met
•D-Gln
•D-Thr
•D-Asp
•D-Pro
•D-His
•D-Trp
•D-Asn
•D-Phe
•D-Leu
•D-Val
•D-Cys
•D-Ser

同型氨基酸

•Har
•HomoCit
•beta-HomoMet
•beta-HomoSer
•D-Har
•D-HomoCit
•beta-HomoPro
•beta-HomoThr
•Hcy
•HomoLeu
•beta-HomoVal
•beta-HomoTrp
•HPh
•HomoPro
•beta-HomoAsp
•beta-HomoTyr
•D-HPh
•D-HomoPro
•beta-HomoAsn
•Azidohomoalanine
•Hse
•beta-HomoIle
•beta-HomoGlu
•beta-HomoAla
•D-Hse
•beta-HomoLeu
•beta-HomoGln
•beta-HomoPhe

特殊氨基酸

•beta-Asp
•3-Thi
•D-Chg
•Cys (pMeBzl)
•D-beta-Asp
•Aib
•Ac6c
•Cys (pMeOBzl)
•gamma-Glu
•Abu
•Dab
•Oic
•D- gamma-Glu
•D-Abu
•Dap
•Tic
•Cys (Cam)
•Hyp
•Pra
•D-Tic
•D-Cys (Cam)
•Phg
•D-Pra
•Cys (Bzl)
•Cys (Acm)
•D-Phg
•Allo-Thr
•Epsilon-Lys
•Cys (tBu)
•Nva
•D-Allo-Thr
•D-Epsilon-Lys
•Cys (StBu)
•D-Nva
•Gly (allyl)
•5-ASA
•Met (O)
•Nle
•D-Gly (allyl)
•Bpa
•D-Met (O)
•D-Nle
•Cys (Pyrene-maleimide)
•Pip
•Cys (SNO)
•Cit
•D-1-Nal
•Nip
•Met (O)₂
•D-Cit
•L-1-Nal
•2-Aze
•D-Met (O)₂
•Orn
•D-2-Nal
•3-Aze
•Lys (Ac)
•D-Orn
•L-2-Nal
•[Psi (CH₂NH)]
•Ac-Lys
•Pen
•D-2-Pal
•[CS-NH]
•Lys (Dde)
•D-Pen
•L-2-Pal
•Se-Met
•Tle
•Cpg
•D-3-Pal
•Se-Cys
•Ser (Octanoic acid)
•Cha
•L-3-pal
•DOPA
•Ser (Lipoic acid)
•D-Cha
•D-4-Pal
•isoGln
•D-Ser (Octanoic acid)
•Chg
•L-4-Pal
•D-isoGln
•Arg (Boc₂)
•Asp-OMe
•D-Glu (OtBu)
•Lys (Z)
•Arg (NO₂)
•Asp-OtBu
•Gln (Trt)
•Ser (Bzl)
•Arg (Z₂)
•Asn (Trt)
•His (Boc)
•Ser (Trt)
•Arg (pbf)
•Cys (MMt)
•His (Trt)
•Ser (tBu)
•D-Arg (pdf)
•Cys (Trt)
•Tyr (propargyl)
•Tyr (tBu)
•Asp (Oall)
•D-Cys (Trt)
•Lys (Boc)
•Asp (OBn)
•Glu (Oall)
•Lys (DMT)
•D-Tyr (tBu)
•Asp (OBzl)
•Glu (OBzl)
•Lys (Fomc)
•Thr (tBu)
•Asp (OMe)
•Glu (OMe)
•Lys (Mtt)
•Trp (Boc)
•Asp (OtBu)
•Glu (OtBu)
•Lys (Trt)
•Trp (Farnesyl)

注意：

1. 以上信息仅供参考，您提供的多肽修饰定制需求将提交至实验室评估。

2. 如有未列入表格中的多肽修饰需求，您可以发邮件至 sales@MedChemExpress.cn 进行咨询。.

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)

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