2. 疾病领域
  3. 消化系统疾病

Digestive system Disease  (消化系统疾病)

胃肠系统疾病涵盖胃肠道疾病，其特征包括舌剥、卡他性炎症和便血等症状。关键的遗传因素包括MIR199A1基因，该基因在与DNA损伤反应和细胞分化途径相关的miRNA中发挥作用。瑞巴派特和吲哚美辛等治疗药物与该疾病相关，主要受累组织包括小肠和肝脏。

Gastrointestinal System Disease encompasses disorders of the stomach and intestines, characterized by symptoms such as peeling tongue, catarrh, and blood in stool. Key genetic involvement includes the MIR199A1 gene, which plays a role in miRNAs associated with DNA damage response and cell differentiation pathways. Therapeutic agents like Rebamipide and Indomethacin are linked to this condition, with affected tissues primarily including the small intestine and liver.

 

Digestive system Disease (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0385
    Gomisin J

    戈米辛J

    		66280-25-9 99.97%
    Gomisin J 是一五味子来源的木脂素，可靶向 eNOS、AMPK (LKB1、CaMKIIβ)、fetuin-A、NF-κB、Nrf2/HO-1 等多个靶点，且能通过血脑屏障。Gomisin J 通过激活 eNOS 增加 NO 生物利用度、激活 AMPK 通路调节脂代谢、抑制 fetuin-A 和 NF-κB 发挥抗炎作用、激活 Nrf2/HO-1 增强抗氧化能力等机制。Gomisin J 具有抗高血压、调节肝脂代谢、减轻脑缺血再灌注损伤等活性，可用于高血压、非酒精性脂肪肝、脑缺血再灌注损伤等研究。
    Gomisin J
  • HY-E70064A
    Helicobacter pylori alpha-1,3-fucosyltransferase

    幽门螺杆菌 α-1,3 - 岩藻糖转移酶

    Helicobacter pylori alpha-1,3-fucosyltransferase (Hp3FT) 催化供体 GDP-岩藻糖与受体 N-乙酰乳糖胺进行糖基加成反应。
    Helicobacter pylori alpha-1,3-fucosyltransferase
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